Design clean rooms using an executable Digital Twin to maximize factory simulation planning

Pharmaceutical manufacturing leaders face growing pressure to meet stringent regulatory requirements, control operating costs and accelerate product release. At the same time, unexpected downtime, reactive monitoring and complex compliance demands increase risk across clean room operations. Traditional design approaches often rely on assumptions and physical testing, making it difficult to balance performance, efficiency and compliance with confidence.

An executable Digital Twin (xDT) helps manufacturers design and optimize clean rooms through virtual simulation. Using tools such as Siemens Simcenter STAR-CCM+, Simcenter Amesim, NX and Plant Simulation, teams can model airflow, particle movement, contaminant removal and equipment layouts to improve contamination control, optimize factory simulation planning and evaluate performance under a range of operating conditions.

By combining the physical and digital worlds, manufacturers can reduce validation and testing efforts, lower operating costs through optimized energy performance and create digital evidence to support compliance with requirements such as EU GMP Annex 1. Teams gain deeper operational insight, respond more effectively to changing conditions and develop proactive strategies that improve performance across the facility.

View the infographic today to learn more.