As AI workloads drive unprecedented increases in data center power demand, the industry is rethinking how electricity is delivered to the rack. This paper explores the advantages, trade-offs, and protection challenges of 2-wire and 3-wire DC power architectures, providing a quantitative comparison of performance, safety, fault behavior, and operational resilience. Through detailed analysis of grounding methods, fault scenarios, energy storage, and protection strategies, it offers practical insights for designing next-generation hyperscale and AI data centers. Discover which architecture is best suited to support the future of high-density digital infrastructure.